Supported by:
World Health Organization (WHO)

Lead Investigator:
Dr. Marie Gilbert Majella, Senior Research Consultant

This global review explores how urinary iodine concentration (UIC) relates to thyroid health, reproductive outcomes, and cognitive development across different populations.

Focus Areas:

• Define UIC thresholds for deficiency and excess
• Assess impact on children, women (15–49 yrs), and pregnant women
• Identify data gaps and population-specific risks

Approach:

• Inclusion of all study types and global data
• Quality assessed using QUIPS, RoB-2, NOS
• Synthesis using SWiM, harvest & albatross plots
• GRADE method for evidence strength