Supported by:
World Health Organization (WHO)

Lead Investigator:

• Dr. Yuvaraj Krishnamoorthy Consultant & Head of Evidence Syntesis Unit

This review aims to determine the most effective HbA1c target values for reducing complications (hypoglycemia, cardiovascular issues, DKA, etc.) in adults with Type 1 Diabetes Mellitus (T1DM).

Focus Areas:

• Identify cut-offs that balance risk of long-term complications vs. hypoglycemia
• Inform updated clinical practice guidelines
• Compare outcomes using direct and network meta-analysis