India’s First Evidence-Based Lung Cancer Treatment Guidelines
PROPUL Evidence LLP is proud to have contributed, in collaboration with experts from MGMCRI and JIPMER, to the Evidence-Based Guidelines on Lung Cancer Treatment and Palliation released by the Ministry of Health & Family Welfare, Government of India, ahead of World Cancer Day. The guidelines were formally released by the Union Health Minister and provide a standardized, evidence-based framework for lung cancer care across India.
Our team worked on the clinical question:
“In patients with small cell lung cancer (SCLC), what is the comparative effectiveness of prophylactic cranial irradiation (PCI) compared with no PCI?”
Using a rigorous systematic review and GRADE-based approach, the guideline panel issued a strong recommendation in favour of PCI for patients with SCLC, based on the overall balance of benefits, harms, feasibility, and acceptability in the Indian context.
We are especially grateful to Dr. Premkumar Ramasubramani for leading the review process with expertise and dedication, and to Dr. Marie Gilbert Majella, Dr. Ambedkar Yadala, and Dr. Pajanivel R for their continuous support and guidance throughout the review. This collaboration reflects the strength of multidisciplinary teamwork in producing high-quality, context-specific evidence for national guideline development.
It has been a privilege for PROPUL Evidence LLP to support indigenously developed, evidence-based recommendations that can strengthen early diagnosis, standardized cancer care, and palliative services across India. We look forward to contributing to more national guideline efforts that place high-quality evidence at the heart of policy and practice.
Read the official release:
https://www.pib.gov.in/PressReleasePage.aspx?PRID=2222810&v=2®=3&lang=2

